Career Opportunities in Immunotherapy

Join our growing team of individuals dedicated to collaboration, life-long learning and seeing a day in which people with cancer live markedly longer and better lives. Syndax Pharmaceuticals, Inc. offers a competitive salary and benefits package. Qualified candidates should submit their resume and cover letter with a statement of interest, availability, and experience in Word or PDF format to: [email protected]. Syndax is an Equal Opportunity Employer.


  • Finance Summer Intern

    At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. Syndax is currently focused on developing an innovative pipeline of combination therapies in multiple cancer indications.

    Our lead product candidate, entinostat, which was granted Breakthrough Therapy designation by the U.S. Food and Drug Administration following positive results from our Phase 2b clinical trial, ENCORE 301, is currently being evaluated in a Phase 3 clinical trial for advanced hormone receptor positive breast cancer, and as a combination therapeutic in Phase 1b/2 clinical trials with Merck & Co., Inc. for non-small cell lung cancer and melanoma, with Genentech, Inc. for TNBC, and with Pfizer Inc. and Merck KGaA, Darmstadt, Germany, for ovarian cancer.

    Concurrently, Syndax is also developing SNDX-6352 (also known as UCB6352), an IND-ready anti-CSF-1R monoclonal antibody, to potentially enhance the body’s immune response on tumors that have shown sensitivity to immunotherapy. We expect to advance SNDX-6352 into the clinic later this year.

    Syndax is headquartered in Waltham, Massachusetts.

    The Finance Intern will support the Accounting Department with the following activities:

    • Help enter invoices and purchase orders into NetSuite, our GL system
    • File invoices and various other documents appropriately
    • Provide help on completing expense reports using Concur
    • Help on other ad hoc projects are needed

    Skills required:

    • Great analytical skills
    • Microsoft Excel
    • Detail oriented personality

    We are looking for someone 3 days per week for the summer and have flexibility on working schedule

  • Senior Administrative Assistant

    Position Description:

    Syndax is currently looking for a dynamic Senior Administrative Assistant to support several members of Senior Management as well as the Human Resources Team. We are a small team people, culturally diverse, with a common goal of always keeping the patient in mind. In this role you will have exposure to all members and all levels of the Syndax team, where you can demonstrate your unique skills and play a critical role in the success of the organization.


    • Responsible for administrative support to/and responding to the needs of the Chief Financial Officer; the VP, Program Management; the Human Resource team and other senior staff as required. Responsibilities include, but are not limited to, the following: scheduling and calendar management, meeting arrangements, manage incoming and outgoing written and verbal correspondence, proactively coordinate team and project team meetings and materials, travel arrangements, compile expense reports, etc.
    • Schedule, coordinate and provide logistical support for internal and external business meetings, workshops, conferences and partnering meetings
    • Communicate collaboratively with staff in functions such as Finance, Regulatory, Project Management, HR, and with Syndax staff located at sites other than headquarters, to ensure resources, information, and projects are coordinated
    • Coordinate the production and dissemination of meeting agendas and other materials, as needed
    • Attend staff meetings; may take meeting minutes for some meetings
    • Coordinate and arrange detailed domestic/international travel schedules and itineraries including airline, hotel, car, restaurant reservations and/or conference registrations
    • Work on ad-hoc projects as assigned: document production, deck creation, research, training and onboarding initiatives, event planning and more
    • Collaborate with other Syndax administrative and operations staff to coordinate activities and provide back-up coverage for company-wide administrative support
    • Be available at occasionally for various off-hours business related tasks
    • Working closely with the Human Resources team, be responsible for creating a positive candidate experience by coordinating recruiting activities such as scheduling candidates, managing logistics on the day of interviews
    • Maintain and prepare reports and organization charts
    • Manage new hire orientations; Ensure that information flows to other functions to enable the new hires successful onboarding
    • Coordinate company-wide events such as the monthly brown bag lunch program, training activities, annual benefits open enrollment and other engagement activities
    • Work closely with the accounting department to ensure employee benefit enrollment is accurate
    • Ensure compliance of human resource and benefit documentation; Maintain employee files


    • AS or BS Degree with at least 5-8 years related experience in progressively responsible administrative roles; experience in a biotech or pharmaceutical organization is a plus
    • Must thrive working in a fast-paced, innovative environment while remaining flexible, proactive, resourceful and efficient. A good sense of humor is critical!
    • Ability to contribute as both an independent, self-starter and a collaborative team member
    • Top-notch organizational skills with strong attention to detail
    • Excellent interpersonal skills and ability to develop important relationships with key stakeholders
    • Excellent verbal and written communication skills, exercising tact, diplomacy and discretion
    • Must have a high degree of professionalism and experience having access to confidential and personal information
    • Excellent computer skills, in particular Microsoft Outlook, Word, Excel and PowerPoint. Prior experience with web-based programs such as GoToMeeting, Concur, Amex Global Business Travel, etc. strongly preferred.
    • Demonstrated multi-tasking and project management skills
    • Willing and able to travel occasionally for business
  • Vice President, Clinical Research and Development

    Position Description:

    Syndax is seeking a strategic minded physician leader for the role of Vice President of Clinical Research & Development. The role will report to Chief Medical Officer. This is an exciting time as we push forward with P3 development activities for our lead program and expansion of our early development pipeline.


    The VP, Clinical Research and Development, will provide leadership for the clinical team and the drug development programs. The successful candidate will provide medical and scientific expertise on the strategy, design, execution and interpretation of data from clinical stage programs relating to the treatment of hematologic malignancies and solid tumors. This leadership role will be responsible for the clinical development function; direct reports include one or more physicians and other Clinical Development functions, depending on the background of the candidate.

    He/she is responsible for ensuring that all studies are conducted with the highest level of ethical and safety standards and are in compliance with GCP and all regulatory policies. Duties include primary interactions with investigators and global monitors, functioning as the medical representative on the integrated project team, and providing medical consultations as needed across the Syndax portfolio of products and studies.

    The individual will take on leadership of all early oncology clinical development programs and partner with CMO on late development activities for entinostat for the breast cancer indication and line extension programs. As a member of the Development Leadership team, he/she will work on the design, execution, data analysis and interpretation and reporting of clinical trials. The individual will interact closely with company management. A genuine interest and understanding of the science, desire to work in a highly collaborative organization, and deep passion about making a difference in the lives of patients are essential.


    • Directly responsible for the clinical development strategy, including the clinical development plans and operational plans, for hematologic malignancies.
    • Design and manage writing of oncology clinical study protocols from first-in-human phase 1 through phase 2 and phase 3 pivotal studies to support regulatory approvals.
    • Present findings internally and externally (such as investigator meetings, regulatory agency meetings) acting as a spokesperson for Syndax relating to the trial/indication.
    • Review and interpret and prepare medical sections of CSR’s and other regulatory documents in collaboration with medical writing to generate study report of clinical trial data, according to GCP.
    • Review and interpret data for annual updates of safety reports, IBs, IND/NDA submissions and responses to questions from regulatory agencies.
    • Collaborate with pre-clinical, clinical operations, translational medicine, regulatory, drug safety, statistics and data management in the development of development strategies and clinical studies; review and provide input on other protocol-related material (CRFs, DMP, SAP, etc.)
    • Lead study team meetings and provide medical guidance to the clinical operations team in the execution of clinical trials.
    • Secure, analyze and report on competitive intelligence related to successful conduct/execution of studies sponsored by other organizations and new data that may impact Syndax studies.
    • Provide mentorship and development opportunities to others within Syndax Pharmaceuticals
    • Responsible for resourcing clinical development programs within functional area.
    • Ensures the highest level of ethical standards are following, in compliance with internal SOPs, regulatory agencies, and laws.


    • An MD degree with Board Certification or Board Eligibility in adult or pediatric oncology or hematology
    • 8+ years of drug development industry experience in hematology/oncology programs, including a thorough understanding of drug development from IND to NDA.
    • Strong leadership experience managing direct reports and influencing in a matrix environment.
    • Candidates must possess effective written and oral communication and influencing skills.
    • Critical traits for success include strategic and proactive thinking, strong scientific and analytical skills, decisiveness and the ability to perform as a respected team member and leader.
    • Ability to work independently to achieve objectives and work on more than one project simultaneously.