Mr. Podlesak joined Domain Associates as a partner in 2007. Prior to Domain, Mr. Podlesak served as the chief executive officer and a member of the board of directors of Cerexa, Inc., which became a wholly–owned subsidiary of Forest Laboratories after Mr. Podlesak led the growth and sale of the company to Forest. Additionally, Mr. Podlesak served as the president and chief executive officer and as a member of the board of directors of Peninsula Pharmaceuticals, and after building the company, led the sale of Peninsula to Johnson and Johnson. Mr. Podlesak was also chief executive officer, founder and board member of Calixa Therapeutics, which was acquired by Cubist, and chairman of Corthera, which was acquired by Novartis AG.
Earlier in his career, Mr. Podlesak served as senior vice president, head of the North American business unit and member of the pharmaceutical executive committee and global leadership team at Novartis AG. Mr. Podlesak also served as vice president and head of the CEC division of Allergan, Inc., and as member of Allergan's North American and global management team. Mr. Podlesak spent the first ten years of his career with SmithKline Beecham (now GlaxoSmithKline plc).
In addition to Syndax, Mr. Podlesak is currently serving as the chairman of the board at Adynxx and Regado Biosciences. Mr. Podlesak received a bachelor’s degree in business administration from Western Illinois University and an M.B.A. degree from Pepperdine University.